All times are in West Africa Time (WAT).
Friday, 18 September
- 19:45 — Monza vs Sassuolo (U-Power Stadium)
Saturday, 19 September
- 14:00 — Bologna vs Torino (Renato Dall’Ara)
- 14:00 — Udinese vs Cagliari (Bluenergy Stadium)
- 17:00 — Roma vs Inter (Stadio Olimpico)
- 19:45 — Venezia vs Lazio (Stadio Pier Luigi Penzo)
Sunday, 20 September
- 11:30 — Fiorentina vs Napoli (Artemio Franchi)
- 14:00 — Frosinone vs Como (Benito Stirpe)
- 14:00 — Parma vs Genoa (Ennio Tardini)
- 17:00 — Juventus vs Atalanta (Allianz Stadium)
- 19:45 — AC Milan vs Lecce (San Siro)
Key matches include Roma vs Inter on Saturday and Juventus vs Atalanta on Sunday, both expected to attract significant attention.