The Commanders controlled their NFC East encounter, recording five sacks against Philadelphia and limiting the Eagles' offensive production.
Quarterback Jayden Daniels finished with 240 total yards and a touchdown, while Rachaad White led Washington's rushing attack with 55 yards and a score. Saquon Barkley scored Philadelphia's only touchdown as the Eagles suffered their sixth consecutive defeat.
Denver also delivered a significant result, overcoming Kansas City 28-24 after scoring 15 unanswered points in the fourth quarter.
Bo Nix led the comeback, throwing for 222 yards and two touchdowns. Jonah Coleman played a decisive role in the winning sequence, catching a 51-yard pass before scoring on a five-yard run with 1:56 remaining.
Patrick Mahomes threw for 321 yards and three touchdowns, but Kansas City could not find a response after Denver's late surge.
Elsewhere, the Detroit Lions handed the Minnesota Vikings their first defeat of the season, winning 19-15. Jared Goff engineered a late winning drive, capped by a seven-yard touchdown pass to Jameson Williams. Jahmyr Gibbs contributed 168 total yards and a touchdown.
The Buffalo Bills defeated the Baltimore Ravens 36-10, with Josh Allen recording 319 total yards and three touchdowns. Baltimore suffered a major setback when quarterback Lamar Jackson left with a thumb injury.
In one of the weekend's most exciting encounters, the Cincinnati Bengals defeated the Tennessee Titans 43-36 in overtime. Joe Burrow delivered a career-best six total touchdowns and threw for 462 yards, leading Cincinnati to a dramatic comeback victory.
The Arizona Cardinals also produced a remarkable comeback, beating the Dallas Cowboys 33-30 in overtime after recovering from a 17-3 half-time deficit. Gardner Minshew helped turn the contest around after replacing Jacob Brissett, while running back Tyler Allgeier recorded 147 rushing yards.
The Pittsburgh Steelers strengthened their position in the AFC North with a 27-6 victory over the Cleveland Browns. Jaylen Warren rushed for 143 yards and a touchdown, while Pittsburgh's defence recorded eight sacks against Deshaun Watson.
The Tampa Bay Buccaneers created history with a 16-0 shutout victory over the Atlanta Falcons despite completing no passes. Baker Mayfield finished with three rushing attempts, while Bucky Irving rushed for 170 yards and a touchdown.
The Las Vegas Raiders overcame the New York Jets 38-33 after recovering from a half-time deficit. Kirk Cousins threw for 247 yards and three touchdowns, while Jets running back Braelon Allen recorded a career-high 147 rushing yards.
The Jacksonville Jaguars recorded one of the weekend's biggest victories, thrashing the Indianapolis Colts 42-7. Trevor Lawrence threw for 210 yards and three touchdowns, while defensive back Rayuan Lane III added a pick-six.
The Los Angeles Rams defeated the Los Angeles Chargers 24-9, extending the Chargers' difficult start to the campaign. Matthew Stafford threw for a touchdown, while Puka Nacua recorded 11 receptions for 80 yards and a score.
The New England Patriots completed the weekend's victories with a 24-19 win over the Miami Dolphins. Drake Maye accounted for three touchdowns as New England recovered from a 13-3 half-time deficit.
Earlier in the week, the Green Bay Packers defeated the Carolina Panthers 27-19 in Thursday's encounter.
Selected Week 8 results
• Washington Commanders: 27-10 Philadelphia Eagles
• Denver Broncos: 28-24 Kansas City Chiefs
• Detroit Lions: 19-15 Minnesota Vikings
• Buffalo Bills: 36-10 Baltimore Ravens
• Cincinnati Bengals: 43-36 Tennessee Titans (OT)
• Arizona Cardinals: 33-30 Dallas Cowboys (OT)
• Pittsburgh Steelers: 27-6 Cleveland Browns
• Tampa Bay Buccaneers: 16-0 Atlanta Falcons
• Las Vegas Raiders: 38-33 New York Jets
• Jacksonville Jaguars: 42-7 Indianapolis Colts
• Los Angeles Rams: 24-9 Los Angeles Chargers
• New England Patriots: 24-19 Miami Dolphins
• Green Bay Packers: 27-19 Carolina Panthers
Week 8 delivered several dramatic finishes, historic defensive performances and significant results in the divisional races as teams continued their push towards the 2026 NFL play-offs.